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🤱 产科与新生儿 · 第5课,共6课 · 7 min

第一个小时:APGAR、保暖、Vitamin K 和血糖

The First Hour: APGAR, Warmth, Vitamin K and Sugar

👶 新生儿在生命的最初几分钟内以四种方式散失热量,而受凉的婴儿会燃烧其葡萄糖和氧气来努力保持温暖。护理的第一个小时主要关乎热力学。

👶 A newborn loses heat four ways in the first minutes of life, and a cold baby burns through its glucose and oxygen trying to stay warm. The first hour of nursing care is mostly about thermodynamics.

💡 核心要点

擦干、保暖、皮肤接触。APGAR 7 至 10 分为正常。出生后不久(最初 6 小时内)给予 Vitamin K,并加上眼膏。24 小时前的黄疸是病理性的;对有风险的婴儿检查血糖。

Dry, warm, skin-to-skin. APGAR 7 to 10 normal. Vitamin K soon after birth (within the first 6 hours), plus eye ointment. Jaundice before 24 hours is pathologic; check glucose in at-risk babies.

🧠 为什么重要

APGAR 评分在出生后 1 分钟和 5 分钟时评估心率、呼吸努力、肌张力、反射应激性和肤色,每项 0 至 2 分;7 至 10 分令人安心,4 至 6 分为中度异常,0 至 3 分为低分。复苏绝不会为了等待评分而延误:当婴儿需要复苏时,复苏在 1 分钟评分之前就开始了。预期的新生儿生命体征:心率 110 至 160,呼吸 30 至 60(不规则,伴有短于 20 秒的短暂暂停),体温 36.5 至 37.5 °C。通过立即擦干、移除湿床单、皮肤接触、戴帽子,并让婴儿远离气流和寒冷表面(蒸发、传导、对流、辐射)来防止热量散失。在股外侧肌 IM 注射 Vitamin K 以预防出血,给予 erythromycin 眼膏以预防新生儿眼炎,并接种第一剂 hepatitis B 疫苗:AAP 推荐在 24 小时内为体重 2,000 g 或以上、医学上稳定的婴儿接种出生剂量,而自 2025 年末以来,当母亲 HBsAg 阴性时,CDC 时间表将出生剂量留给个人决定;如果母亲 HBsAg 阳性,则在出生后 12 小时内给予疫苗和 hepatitis B 免疫球蛋白。对有风险的婴儿(母亲患糖尿病的婴儿、大于或小于胎龄的婴儿、早产儿、受冷应激的婴儿)筛查低血糖;颤抖、无力、喂养不良和呼吸暂停是其征象,血糖低于约 40 至 45 mg/dL 时用早期喂养或 IV dextrose 治疗。出生后 24 小时内的黄疸是病理性的(溶血、ABO 或 Rh 不合);24 小时后的黄疸通常是生理性的。光疗:戴上眼罩,遮盖生殖器,经常翻身,保持水分并注意体温。脐带护理保持干燥和清洁;脐带在 1 至 2 周内脱落。会让父母担心的预期表现:粟粒疹、先天性皮肤黑素细胞增多症(以前称为蒙古斑:良性的蓝灰色斑片,记录下来以免被误认为瘀伤)、出生后第一天的手足发绀、跨越颅缝的产瘤,以及吸吮、觅食、Moro、抓握和 Babinski 反射。

APGAR scores at 1 and 5 minutes rate heart rate, respiratory effort, muscle tone, reflex irritability and color from 0 to 2 each; 7 to 10 is reassuring, 4 to 6 is moderately abnormal, and 0 to 3 is low. Resuscitation is never delayed to wait for the score: when a baby needs it, it starts before the 1-minute score. Expected newborn vital signs: heart rate 110 to 160, respirations 30 to 60 (irregular, with brief pauses under 20 seconds), temperature 36.5 to 37.5 °C. Prevent HEAT LOSS by drying immediately, removing wet linen, skin-to-skin contact, a cap, and keeping the infant away from drafts and cold surfaces (evaporation, conduction, convection, radiation). Give VITAMIN K intramuscularly in the vastus lateralis to prevent bleeding, ERYTHROMYCIN eye ointment to prevent ophthalmia neonatorum, and the first HEPATITIS B vaccine: AAP recommends a birth dose within 24 hours for medically stable infants weighing 2,000 g or more, while since late 2025 the CDC schedule leaves the birth dose to individual decision-making when the mother is HBsAg-negative; if the mother is HBsAg-positive, the vaccine and hepatitis B immune globulin are given within 12 hours of birth. Screen at-risk infants (of diabetic mothers, large or small for dates, preterm, cold-stressed) for HYPOGLYCEMIA; jitteriness, lethargy, poor feeding and apnea are signs, and a glucose below about 40 to 45 mg/dL is treated with early feeding or IV dextrose. JAUNDICE in the first 24 hours is PATHOLOGIC (hemolysis, ABO or Rh incompatibility); jaundice after 24 hours is usually physiologic. Phototherapy: eye shields on, genitals covered, turn frequently, maintain hydration and watch temperature. Umbilical cord care is dry and clean; it falls off in 1 to 2 weeks. Expected findings that alarm parents: milia, congenital dermal melanocytosis (formerly called Mongolian spots: benign blue-gray patches, documented so they are not mistaken for bruises), acrocyanosis in the first day, caput succedaneum crossing suture lines, and the sucking, rooting, Moro, grasp and Babinski reflexes.

🏥 真实场景

🧢 一名母亲患糖尿病的大于胎龄婴儿在出生 2 小时时出现颤抖。护士检查足跟血血糖:32 mg/dL。由于婴儿有症状,护士立即通知医生,并按规程准备 IV dextrose。如果婴儿能安全吸吮,可以给予喂养,但喂养绝不能延误 IV 治疗。单独喂养(或 dextrose 凝胶)适用于无症状的低血糖。治疗后复查血糖。母亲的高血糖使胎儿胰岛素升高,而出生时供应被切断了。考试将“母亲患糖尿病的婴儿”与“颤抖”配对,并每次都期望你“检查血糖”。

🧢 A large-for-dates infant of a diabetic mother is jittery at 2 hours of age. The nurse checks a heel-stick glucose: 32 mg/dL. Because the baby has symptoms, the nurse notifies the provider immediately and prepares for IV dextrose per protocol. A feeding may be offered if the baby can suck safely, but it must not delay IV treatment. Feeding (or dextrose gel) alone is the approach for low glucose without symptoms. The glucose is rechecked after treatment. Maternal hyperglycemia drove fetal insulin high, and the supply was cut at birth. The exam pairs 'infant of a diabetic mother' with 'jittery' and expects 'check the glucose' every time.

📌 要点总结

  • APGAR 在 1 分钟和 5 分钟时评估;7 至 10 分为正常APGAR at 1 and 5 minutes; 7 to 10 is normal
  • 热量散失:蒸发、传导、对流、辐射;擦干并覆盖Heat loss: evaporation, conduction, convection, radiation; dry and cover
  • Vitamin K IM 注射、erythromycin 眼膏、hepatitis B 疫苗;24 小时内的黄疸是病理性的Vitamin K IM, erythromycin eyes, hepatitis B; jaundice under 24 hours is pathologic

📖 本课术语

APGAR评分 (APGAR score): 新生儿在1分钟和5分钟时对心率、呼吸、肌张力、反射和肤色的评分;7至10为正常。

APGAR(新生儿评分) (APGAR (newborn score)): Appearance(外观,肤色)、Pulse(脉搏)、Grimace(鬼脸,反射反应)、Activity(活动,肌张力)、Respiration(呼吸):五项新生儿征象,每项按0至2分评分,在1分钟和5分钟时进行。

新生儿胆红素 (Newborn bilirubin): 生理性黄疸在24小时后出现,峰值约为5到6 mg/dL,出现在第3到5天;出生后24小时内出现的黄疸为病理性黄疸,光疗阈值遵循按小时划分的AAP图表,水平接近20到25有发生核黄疸的风险。

新生儿血糖 (Newborn blood glucose): 新生儿血糖低于约40到45 mg/dL为低血糖;糖尿病母亲的婴儿、相对于胎龄过大或过小、早产或受冷应激的婴儿需接受筛查,出现抖动、喂养不良或呼吸暂停时需喂养或静脉给予葡萄糖。

✅ 自我测试

一名新生儿心率为 120,哭声有力,屈曲良好,吸引时做鬼脸,身体粉红而手足发青,评估时间为出生后 1 分钟。APGAR 评分是多少?A newborn has a heart rate of 120, a strong cry, good flexion, a grimace to suction and a pink body with blue hands and feet at 1 minute. What is the APGAR score?
  1. 7
  2. 10
  3. 6
  4. 8

答案: D · 8

心率 2 分,呼吸努力 2 分,肌张力 2 分,反射应激性 1 分(做鬼脸),肤色 1 分(手足发绀)= 8 分。7 分来自将发青的手足评为肤色 0 分;只有全身发青或苍白的婴儿才得 0 分,因此手足发绀得 1 分。

Heart rate 2, respiratory effort 2, tone 2, reflex irritability 1 (grimace), color 1 (acrocyanosis) = 8. 7 comes from scoring the blue hands and feet as 0 for color; only a completely blue or pale infant scores 0, so acrocyanosis earns 1.

哪项新生儿发现需要立即报告?Which newborn finding requires immediate reporting?
  1. 骶部蓝灰色斑片Blue-gray patches on the sacrum
  2. 出生 12 小时时发现皮肤和巩膜发黄Yellow skin and sclera noted at 12 hours of age
  3. 呼吸频率 48,伴有 5 秒的短暂暂停A respiratory rate of 48 with brief 5-second pauses
  4. 鼻子上的小白色丘疹Small white papules on the nose

答案: B · 出生 12 小时时发现皮肤和巩膜发黄

出生后 24 小时内的黄疸是病理性的,提示溶血;其他发现都是正常变异。呼吸频率 48 并伴有 5 秒的短暂暂停属于预期的新生儿模式,并不像早期黄疸那样提示紧急问题。

Jaundice within the first 24 hours is pathologic and suggests hemolysis; the other findings are normal variants. A respiratory rate of 48 with brief 5-second pauses is within the expected newborn pattern and does not signal the urgent problem that early jaundice does.

护士为什么要立即擦干新生儿并移除湿毯子?Why does the nurse dry a newborn immediately and remove wet blankets?
  1. 为了准备 Vitamin K 注射To prepare for the vitamin K injection
  2. 为了防止蒸发散热To prevent heat loss by evaporation
  3. 为了改善 APGAR 肤色评分To improve APGAR color scoring
  4. 为了刺激哭泣To stimulate crying

答案: B · 为了防止蒸发散热

湿皮肤的蒸发散热是最初几分钟内最大的散热来源;冷应激会增加氧气和葡萄糖的需求。擦干确实能刺激哭泣和呼吸,但那是附带的好处;移除湿毯子只是为了阻止热量散失。

Evaporative heat loss from wet skin is the largest source of cooling in the first minutes; cold stress raises oxygen and glucose demands. Drying does stimulate crying and breathing, but that is a side benefit; removing the wet blankets serves only to stop heat loss.

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